An-Najah University Journal for Research - A (Natural Sciences)

Effect of “Polypharmacy” and “Frequency of Drug Dosing” on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine

Article info

2002-09-18
2003-05-25
2003-05-25
155 - 165

Keywords

Abstract

The objective of this study was to investigate the influence of polypharmacy and frequency of drug dosing on the rate of compliance among hypertensive and diabetic patients in the Palestinian community. The rate of compliance of 321 hypertensive and diabetic patients was assessed using graded questionnaire. The overall rate of compliance for the tested sample was 42.1%. Both, diabetic and hypertensive patients tend to have better compliance and less noncompliance when the number of medications is decreased. The best rate of compliance in both cases was obtained when patients have simple one drug regimen. Both, diabetic and hypertensive patients tend to have better compliance on once daily dosing (ODD) versus multiple daily dosing (MDD). However, diabetic but not hypertensive patients tend to have better compliance on once daily dosing versus twice daily dosing. These results indicate that although once daily dosing is associated with higher compliance but it is not always the best especially in treatment of hypertension as the treatment of some type of hypertension requirs more than one drug more daily doses, depends on the type of hypertension, as well as dirbetic melitiies. These results should encourage physicians in the hypertension and diabetes mellitus clinics of the Palestinian Ministry of Health (MOH) to minimize the number of prescribed medications to improve compliance, therapeutic outcome and to minimize cost.

Recommended Citation

Sweileh, W., Aker, O., & Hamooz, S. (2003). Effect of “Polypharmacy” and “Frequency of Drug Dosing” on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine. An-Najah University Journal for Research - A (Natural Sciences), 17(2), 155–165. https://doi.org/10.35552/anujr.a.17.2.642
[1]W. Sweileh, O. Aker, and S. Hamooz, “Effect of ‘Polypharmacy’ and ‘Frequency of Drug Dosing’ on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine,” An-Najah University Journal for Research - A (Natural Sciences), vol. 17, no. 2, pp. 155–165, May 2003, doi: 10.35552/anujr.a.17.2.642.
Sweileh, Waleed, et al. “Effect of ‘Polypharmacy’ and ‘Frequency of Drug Dosing’ on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine.” An-Najah University Journal for Research - A (Natural Sciences), vol. 17, no. 2, May 2003, pp. 155–65. Crossref, https://doi.org/10.35552/anujr.a.17.2.642.
1.Sweileh W, Aker O, Hamooz S. Effect of “Polypharmacy” and “Frequency of Drug Dosing” on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine. An-Najah University Journal for Research - A (Natural Sciences) [Internet]. 2003 May;17(2):155–65. Available from: http://dx.doi.org/10.35552/anujr.a.17.2.642
Sweileh, Waleed, Ola Aker, and Saeed Hamooz. “Effect of ‘Polypharmacy’ and ‘Frequency of Drug Dosing’ on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine.” An-Najah University Journal for Research - A (Natural Sciences) 17, no. 2 (May 2003): 155–65. https://doi.org/10.35552/anujr.a.17.2.642.

تأثير تعدد الأدوية و الجرعات الدوائية على الأنضباط الدوائي بين مرضى الضغط والسكري: دراسة مسحية في ‏فلسطين

معلومات المقال

2002-09-18
2003-05-25
2003-05-25
155 - 165

الكلمات الإفتتاحية

الملخص

هدف هذه الدراسة هو بحث تأثير تعدد الأدوية والجرعات الدوائية على الأنضباط الدوائي بين مرضى الضغط والسكري في المجتمع الفلسطيني. تمت معاينة الأنضباط الدوائي على 321 مريضا"" حيث كان معدل الأنضباط الدوائي الجيد يساوي 42,1%. عند مرضى الضغط والسكري كان الأنضباط الدوائي أفضل حيثما قل عدد الأدوية المستعملة. الأنضباط الدوائي كان أفضل ما يمكن عندما كان عدد الأدوية المستعملة هو واحد. عند مرضى الضغط والسكري كان الأنضباط الدوائي أفضل عندما كانت عدد الجرعات الدوائية هي واحدة يوميا"" مقارنة"" بعدة جرعات يوميا"". ولكن, عند مرضى السكري وليس الضغط كان معدل الانضباط الدوائي مع الجرعة الوحدة يوميا"" أفضل من جرعتين يوميا"". هذه النتائج تشير الى أنة مع الرغم أن الجرعة الواحدة يوميا"" مصحوبة بمعدل انضباط دوائي مرتفع الا أنة ليس دائما"" الأفضل وبالذات عند مرضى الضغط. حيث أن العلاج وخاصة لمرضى ضغط الدم يتطلب في كثير من الاحيان استعمال أكثر من دواء واحد، وذلك حسب نوع ضغط الدم الذي يعاني منه. كما أن داء السكري قد يتطلب في بعض الأحيان أكثر من نوع من الأدوية أو أكثر من جرعة واحدة يومياً. هذه النتائج يجب أن تشجع الأطباء العاملين في عيادات السكري والضغط في وزارة الصحة الفلسطينية أن يقللوا من عدد الأدوية الموصوفة لتحسين الأنضباط الدوائي والعلاجي ولتخفيف التكاليف.

Recommended Citation

Sweileh, W., Aker, O., & Hamooz, S. (2003). Effect of “Polypharmacy” and “Frequency of Drug Dosing” on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine. An-Najah University Journal for Research - A (Natural Sciences), 17(2), 155–165. https://doi.org/10.35552/anujr.a.17.2.642
[1]W. Sweileh, O. Aker, and S. Hamooz, “Effect of ‘Polypharmacy’ and ‘Frequency of Drug Dosing’ on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine,” An-Najah University Journal for Research - A (Natural Sciences), vol. 17, no. 2, pp. 155–165, May 2003, doi: 10.35552/anujr.a.17.2.642.
Sweileh, Waleed, et al. “Effect of ‘Polypharmacy’ and ‘Frequency of Drug Dosing’ on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine.” An-Najah University Journal for Research - A (Natural Sciences), vol. 17, no. 2, May 2003, pp. 155–65. Crossref, https://doi.org/10.35552/anujr.a.17.2.642.
1.Sweileh W, Aker O, Hamooz S. Effect of “Polypharmacy” and “Frequency of Drug Dosing” on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine. An-Najah University Journal for Research - A (Natural Sciences) [Internet]. 2003 May;17(2):155–65. Available from: http://dx.doi.org/10.35552/anujr.a.17.2.642
Sweileh, Waleed, Ola Aker, and Saeed Hamooz. “Effect of ‘Polypharmacy’ and ‘Frequency of Drug Dosing’ on Rate of Compliance among Diabetic and Hypertensive Patients: A Survey Study in Palestine.” An-Najah University Journal for Research - A (Natural Sciences) 17, no. 2 (May 2003): 155–65. https://doi.org/10.35552/anujr.a.17.2.642.

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