Electrophysiological Assessment of Diabetic Neuropathy Improvements by using Insulin and Thiamine
Authors:
Article info
2001-05-29
2002-05-07
2002-05-07
39 - 55
Keywords
Abstract
Two groups of (type II) non-insulin dependent diabetes mellitus (NIDDM) patients were assisted electophysiologly for the neuropathy of their peripheral nerves and compared with the control group. The assessments aimed to evaluate the levels of improvements that may occur in the functions of seven peripheral nerves by using insulin (group 1) and thiamine (group 2) as a treatment modalities. The obtained results of the first visit of the patients of both groups showed significant changes in the recordings of the examined parameters (latency, conductive velocity and amplitude) of the peripheral nerves compared to the recordings of the control group. The nerves conduction study (NCS) of the newly diagnosed type II diabetic patients who were shifted to insulin gave statistical significant variable improvements at the 12 month of re-examination and in the three parameters of all the tested nerves at the 18 month of re-examination, compared to the first visit of the patients. The effectiveness of thiamine (vit. B1) on the type II diabetic patients seems to be used for the first time, in the present study. The obtained results showed improvement in the tested parameters of three nerves only, namely the median and ulnar sensory nerves in addition to the sural nerves compared to the first visit records of the patients. Key words: Insulin and Thiamine Effectiveness on Neuropathy of type II diabetic patients.
Muflih, I. W., Abdul-Kareem, A. M., & Al-Sharify, G. A. (2002). Electrophysiological Assessment of Diabetic Neuropathy Improvements by using Insulin and Thiamine. An-Najah University Journal for Research - A (Natural Sciences), 16(1), 39–55. https://doi.org/10.35552/anujr.a.16.1.661
[1]I. W. Muflih, A. M. Abdul-Kareem, and G. A. Al-Sharify, “Electrophysiological Assessment of Diabetic Neuropathy Improvements by using Insulin and Thiamine,” An-Najah University Journal for Research - A (Natural Sciences), vol. 16, no. 1, pp. 39–55, May 2002, doi: 10.35552/anujr.a.16.1.661.
Muflih, I. W., et al. “Electrophysiological Assessment of Diabetic Neuropathy Improvements by Using Insulin and Thiamine.” An-Najah University Journal for Research - A (Natural Sciences), vol. 16, no. 1, May 2002, pp. 39–55. Crossref, https://doi.org/10.35552/anujr.a.16.1.661.
1.Muflih IW, Abdul-Kareem AM, Al-Sharify GA. Electrophysiological Assessment of Diabetic Neuropathy Improvements by using Insulin and Thiamine. An-Najah University Journal for Research - A (Natural Sciences) [Internet]. 2002 May;16(1):39–55. Available from: http://dx.doi.org/10.35552/anujr.a.16.1.661
Muflih, I. W., A.M. Abdul-Kareem, and G.A. Al-Sharify. “Electrophysiological Assessment of Diabetic Neuropathy Improvements by Using Insulin and Thiamine.” An-Najah University Journal for Research - A (Natural Sciences) 16, no. 1 (May 2002): 39–55. https://doi.org/10.35552/anujr.a.16.1.661.
دراسة الكترو- فسيولوجية للتحسن الوظيفي للأعصاب المحيطية المعتلة باستعمال الأنسولين والثيامين في مرضى داء السكري
المؤلفون:
معلومات المقال
2001-05-29
2002-05-07
2002-05-07
39 - 55
الكلمات الإفتتاحية
الملخص
يعتبر اعتلال الأعصاب المحيطية المصاحبة لداء السكري حقلاً خصباً لاهتمام الباحثين والأطباء وخاصة في البحث عن الطرق الناجعة للعلاج وفي هذا الصدد تم دراسة التغيرات في وظائف سبعة أعصاب بالطرق الكهرو-فسيولوجية، وذلك باستدلال سرعة نقل الايعازات العصبية وقياس فترة الكمون الحسي والحركي بالإضافة إلى المدى الكامل للاستجابة العصبية وتم اختيار مجموعتين من مرضى داء السكري غير المعتمد على الأنسولين (Type II)، المجموعة الأولى حولت الى الأنسولين بينما أعطيت المجموعة الثانية فيتامين ب وتم مقارنة التغيرات الحاصلة في وظائف الأعصاب مع مجموعة ثالثة من الأشخاص الأصحاء، ولقد تم متابعة التحسن في وظائف الأعصاب لمدة ثمانية عشر شهراً. لقد برهنت نتائج المجموعة الأولى ان التحسن في الأداء الوظيفي للأعصاب الحركية والحسية كان ذا مدلولاً إحصائياً واضحاً بينما كان التحسن في الأداء الوظيفي للمجموعة الثانية واضحاً في أداء الأعصاب الحسية اكثر منها في أداء الأعصاب الحركية.
Muflih, I. W., Abdul-Kareem, A. M., & Al-Sharify, G. A. (2002). Electrophysiological Assessment of Diabetic Neuropathy Improvements by using Insulin and Thiamine. An-Najah University Journal for Research - A (Natural Sciences), 16(1), 39–55. https://doi.org/10.35552/anujr.a.16.1.661
[1]I. W. Muflih, A. M. Abdul-Kareem, and G. A. Al-Sharify, “Electrophysiological Assessment of Diabetic Neuropathy Improvements by using Insulin and Thiamine,” An-Najah University Journal for Research - A (Natural Sciences), vol. 16, no. 1, pp. 39–55, May 2002, doi: 10.35552/anujr.a.16.1.661.
Muflih, I. W., et al. “Electrophysiological Assessment of Diabetic Neuropathy Improvements by Using Insulin and Thiamine.” An-Najah University Journal for Research - A (Natural Sciences), vol. 16, no. 1, May 2002, pp. 39–55. Crossref, https://doi.org/10.35552/anujr.a.16.1.661.
1.Muflih IW, Abdul-Kareem AM, Al-Sharify GA. Electrophysiological Assessment of Diabetic Neuropathy Improvements by using Insulin and Thiamine. An-Najah University Journal for Research - A (Natural Sciences) [Internet]. 2002 May;16(1):39–55. Available from: http://dx.doi.org/10.35552/anujr.a.16.1.661
Muflih, I. W., A.M. Abdul-Kareem, and G.A. Al-Sharify. “Electrophysiological Assessment of Diabetic Neuropathy Improvements by Using Insulin and Thiamine.” An-Najah University Journal for Research - A (Natural Sciences) 16, no. 1 (May 2002): 39–55. https://doi.org/10.35552/anujr.a.16.1.661.
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