Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report
Authors:
Article info
2025-07-17
2025-12-11
2025-12-21
None - None
Keywords
- case
- mass;
- Metastasis;
- Peri-splenic
- Report
- B2
- thymoma;
- Gravis;
- Myasthenia
- Recurrence;
Abstract
Background: Thymomas are rare epithelial tumors of the thymus. Extra-thoracic metastasis is exceptional and typically involves the liver, bone, or soft tissues. Peri-splenic recurrence is exceedingly rare. Case presentation: A 42-year-old female previously treated for thymoma and pleural metastases presented six years later with a peri-splenic mass. CT-guided core biopsy and immunohistochemistry (p40, Pan-CK, TdT, CD3) confirmed metastatic B2 thymoma. Conclusion: This case highlights an unusual pattern of abdominal recurrence and underscores the value of immunohistochemistry in differentiating thymoma metastasis from lymphoma.
Sweileh, M. W., Zeer, Z. M. M., Swaileh, M., Dmaidi, L., Khader, M., & Qamhia, N. (2025). Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report. Palestinian Medical and Pharmaceutical Journal, 11(4). https://doi.org/10.59049/2790-0231.11.4.2719
Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report
المؤلفون:
معلومات المقال
2025-07-17
2025-12-11
2025-12-21
None - None
الكلمات الإفتتاحية
- case
- mass;
- Metastasis;
- Peri-splenic
- Report
- B2
- thymoma;
- Gravis;
- Myasthenia
- Recurrence;
الملخص
Background: Thymomas are rare epithelial tumors of the thymus. Extra-thoracic metastasis is exceptional and typically involves the liver, bone, or soft tissues. Peri-splenic recurrence is exceedingly rare. Case presentation: A 42-year-old female previously treated for thymoma and pleural metastases presented six years later with a peri-splenic mass. CT-guided core biopsy and immunohistochemistry (p40, Pan-CK, TdT, CD3) confirmed metastatic B2 thymoma. Conclusion: This case highlights an unusual pattern of abdominal recurrence and underscores the value of immunohistochemistry in differentiating thymoma metastasis from lymphoma.
Sweileh, M. W., Zeer, Z. M. M., Swaileh, M., Dmaidi, L., Khader, M., & Qamhia, N. (2025). Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report. Palestinian Medical and Pharmaceutical Journal, 11(4). https://doi.org/10.59049/2790-0231.11.4.2719
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