Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.)

Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report

Article info

2025-07-17
2025-12-11
2025-12-21
None - None

Keywords

  • case
  • mass;
  • Metastasis;
  • Peri-splenic
  • Report
  • B2
  • thymoma;
  • Gravis;
  • Myasthenia
  • Recurrence;

Abstract

Background: Thymomas are rare epithelial tumors of the thymus. Extra-thoracic metastasis is exceptional and typically involves the liver, bone, or soft tissues. Peri-splenic recurrence is exceedingly rare. Case presentation: A 42-year-old female previously treated for thymoma and pleural metastases presented six years later with a peri-splenic mass. CT-guided core biopsy and immunohistochemistry (p40, Pan-CK, TdT, CD3) confirmed metastatic B2 thymoma. Conclusion: This case highlights an unusual pattern of abdominal recurrence and underscores the value of immunohistochemistry in differentiating thymoma metastasis from lymphoma.

Recommended Citation

Sweileh, M. W., Zeer, Z. M. M., Swaileh, M., Dmaidi, L., Khader, M., & Qamhia, N. (2025). Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report. Palestinian Medical and Pharmaceutical Journal, 11(4). https://doi.org/10.59049/2790-0231.11.4.2719

Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report

معلومات المقال

2025-07-17
2025-12-11
2025-12-21
None - None

الكلمات الإفتتاحية

  • case
  • mass;
  • Metastasis;
  • Peri-splenic
  • Report
  • B2
  • thymoma;
  • Gravis;
  • Myasthenia
  • Recurrence;

الملخص

Background: Thymomas are rare epithelial tumors of the thymus. Extra-thoracic metastasis is exceptional and typically involves the liver, bone, or soft tissues. Peri-splenic recurrence is exceedingly rare. Case presentation: A 42-year-old female previously treated for thymoma and pleural metastases presented six years later with a peri-splenic mass. CT-guided core biopsy and immunohistochemistry (p40, Pan-CK, TdT, CD3) confirmed metastatic B2 thymoma. Conclusion: This case highlights an unusual pattern of abdominal recurrence and underscores the value of immunohistochemistry in differentiating thymoma metastasis from lymphoma.

Recommended Citation

Sweileh, M. W., Zeer, Z. M. M., Swaileh, M., Dmaidi, L., Khader, M., & Qamhia, N. (2025). Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report. Palestinian Medical and Pharmaceutical Journal, 11(4). https://doi.org/10.59049/2790-0231.11.4.2719

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