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Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.)

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Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.) Indexed in Scopus since 2022
CiteScore 1.0
Indexed since 2022
First decision 7 Days
Submission to acceptance 45 Days
Acceptance to publication 14 Days
Acceptance rate 8%
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In Press Case report
Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.) / Volume 11, Issue 4, 2026 December

Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report

Moutaz W. Sweileh , Zahraa M. M. Zeer , Mamoun Swaileh , Laila Dmaidi , Mohammad Khader , Naim Qamhia
Published
2025-12-21
DOI
10.59049/2790-0231.11.4.2719
Full text

Keywords

  • case
  • mass;
  • Metastasis;
  • Peri-splenic
  • Report
  • B2
  • thymoma;
  • Gravis;
  • Myasthenia
  • Recurrence;

Abstract

Background: Thymomas are rare epithelial tumors of the thymus. Extra-thoracic metastasis is exceptional and typically involves the liver, bone, or soft tissues. Peri-splenic recurrence is exceedingly rare. Case presentation: A 42-year-old female previously treated for thymoma and pleural metastases presented six years later with a peri-splenic mass. CT-guided core biopsy and immunohistochemistry (p40, Pan-CK, TdT, CD3) confirmed metastatic B2 thymoma. Conclusion: This case highlights an unusual pattern of abdominal recurrence and underscores the value of immunohistochemistry in differentiating thymoma metastasis from lymphoma.

Article history

Received
2025-07-17
Accepted
2025-12-11
Available online
2025-12-21
قيد النشر Case report
Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.) / Volume 11, Issue 4, 2026 كانون أول

Metastatic B2 Thymoma in a Patient with Myasthenia Gravis Presenting as a Peri-splenic Mass: A Rare Case Report

Moutaz W. Sweileh , Zahraa M. M. Zeer , Mamoun Swaileh , Laila Dmaidi , Mohammad Khader , Naim Qamhia
Published
2025-12-21
DOI
10.59049/2790-0231.11.4.2719
البحث كاملا

الكلمات الإفتتاحية

  • case
  • mass;
  • Metastasis;
  • Peri-splenic
  • Report
  • B2
  • thymoma;
  • Gravis;
  • Myasthenia
  • Recurrence;

الملخص

Background: Thymomas are rare epithelial tumors of the thymus. Extra-thoracic metastasis is exceptional and typically involves the liver, bone, or soft tissues. Peri-splenic recurrence is exceedingly rare. Case presentation: A 42-year-old female previously treated for thymoma and pleural metastases presented six years later with a peri-splenic mass. CT-guided core biopsy and immunohistochemistry (p40, Pan-CK, TdT, CD3) confirmed metastatic B2 thymoma. Conclusion: This case highlights an unusual pattern of abdominal recurrence and underscores the value of immunohistochemistry in differentiating thymoma metastasis from lymphoma.

Article history

تاريخ التسليم
2025-07-17
تاريخ القبول
2025-12-11
Available online
2025-12-21