Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.)

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Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.) Indexed in Scopus since 2022
CiteScore 1.0
Indexed since 2022
First decision 7 Days
Submission to acceptance 45 Days
Acceptance to publication 14 Days
Acceptance rate 8%

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Original full research article

The mucinous ovarian cancer: classification and clinical use of cancer biomarkers for diagnosis

Published
2018-08-29
Pages
55 - 58
Full text

Keywords

  • Jordan
  • Women
  • CEA
  • serology
  • Ca125
  • screening
  • Mucinous ovarian cancer (MOC)

Abstract

The aims of the study were to examine the prevalence of positive mucinous ovarian carcinoma (MOC) at different stages as well as to investigate the age at diagnosis and histological type, and to assess the correlation between the carcinoembryonic antigen/ cancer antigen 125 (CEA/CA 125) tests and the diagnosis of ovarian cancers retrospectively, to promote the prognosis and patient’s health outcome. Descriptive a cross-sectional correlational design was used to examine the prevalence of positive ovarian cancer over a period of seven years of follow-up between 2010 and 2016. All study analysis was performed using SPSS version 22. P<0.05 was taken to indicate a statistically significant value. We found that about 70% of cases showed elevation of CEA marker and about 95% of them showed elevation of Ca125. The age-specific incidence rate increased greatly in women aged 50 years or older. The majority of the patients had stage III or IV disease. Our study results can be used as a detection method of possible new ovarian cancer cases in an early stage and would provide a quick non-invasive screening method for women with strong risk factors such as old age, smoking, family history, history of other tumors and obesity.

Article history

Received
2018-07-01
Accepted
2018-08-29
بحث أصيل كامل

The mucinous ovarian cancer: classification and clinical use of cancer biomarkers for diagnosis

Published
2018-08-29
الصفحات
55 - 58
البحث كاملا

الكلمات الإفتتاحية

  • Jordan
  • Women
  • CEA
  • serology
  • Ca125
  • screening
  • Mucinous ovarian cancer (MOC)

الملخص

The aims of the study were to examine the prevalence of positive mucinous ovarian carcinoma (MOC) at different stages as well as to investigate the age at diagnosis and histological type, and to assess the correlation between the carcinoembryonic antigen/ cancer antigen 125 (CEA/CA 125) tests and the diagnosis of ovarian cancers retrospectively, to promote the prognosis and patient’s health outcome. Descriptive a cross-sectional correlational design was used to examine the prevalence of positive ovarian cancer over a period of seven years of follow-up between 2010 and 2016. All study analysis was performed using SPSS version 22. P<0.05 was taken to indicate a statistically significant value. We found that about 70% of cases showed elevation of CEA marker and about 95% of them showed elevation of Ca125. The age-specific incidence rate increased greatly in women aged 50 years or older. The majority of the patients had stage III or IV disease. Our study results can be used as a detection method of possible new ovarian cancer cases in an early stage and would provide a quick non-invasive screening method for women with strong risk factors such as old age, smoking, family history, history of other tumors and obesity.

Article history

تاريخ التسليم
2018-07-01
تاريخ القبول
2018-08-29