Stenotrophomonas maltophilia infections: Experience from a tertiary care teaching hospi-tal in Eastern India
Keywords
- levofloxacin
- Ventilator-associated pneumonia
- Stenotrophomonas maltophilia (SM)
Abstract
Stenotrophomonas maltophilia, a gram-negative nonfermenter, is ubiquitous in the envi-ronment and has the propensity to colonize devices and even the respiratory tract. The organ-ism shows intrinsic resistance to multiple drugs commonly used in hospitals, like cephalo-sporins, carbapenems, and aminoglycosides, thus selecting this organism from endogenous patient flora. Here we conducted a retrospective study presented as a case series to share our experience in our setup. We encountered 9 cases during 1 year, most sensitive to levofloxa-cin and minocycline. All the cases apart from two were discharged successfully following the appropriate regimen. The mean age of patients was 50 years, and most patients had a history of long-standing diabetes. Most of the cases were admitted to ICU and were on ventilators. The organism commonly causes ventilator-associated pneumonia in our series. Our area lacks studies on this organism, which is rising in prevalence. Thus, further large-scale studies are needed to ponder this infection's prevalence and increasing resistance of this organism to TMP/SMX (Cotrimoxazole), the drug of choice in this infection.
Article history
- Received
- 2022-05-19
- Accepted
- 2023-01-10
Stenotrophomonas maltophilia infections: Experience from a tertiary care teaching hospi-tal in Eastern India
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Stenotrophomonas maltophilia infections: Experience from a tertiary care teaching hospi-tal in Eastern India
الكلمات الإفتتاحية
- levofloxacin
- Ventilator-associated pneumonia
- Stenotrophomonas maltophilia (SM)
الملخص
Stenotrophomonas maltophilia, a gram-negative nonfermenter, is ubiquitous in the envi-ronment and has the propensity to colonize devices and even the respiratory tract. The organ-ism shows intrinsic resistance to multiple drugs commonly used in hospitals, like cephalo-sporins, carbapenems, and aminoglycosides, thus selecting this organism from endogenous patient flora. Here we conducted a retrospective study presented as a case series to share our experience in our setup. We encountered 9 cases during 1 year, most sensitive to levofloxa-cin and minocycline. All the cases apart from two were discharged successfully following the appropriate regimen. The mean age of patients was 50 years, and most patients had a history of long-standing diabetes. Most of the cases were admitted to ICU and were on ventilators. The organism commonly causes ventilator-associated pneumonia in our series. Our area lacks studies on this organism, which is rising in prevalence. Thus, further large-scale studies are needed to ponder this infection's prevalence and increasing resistance of this organism to TMP/SMX (Cotrimoxazole), the drug of choice in this infection.
Article history
- تاريخ التسليم
- 2022-05-19
- تاريخ القبول
- 2023-01-10