Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.)

The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study

Article info

2022-01-14
2023-01-12
337 - 342

Keywords

  • Sleep Curtailment; Insulin Resistance; Androgens
  • Leptin

Abstract

Aims: Sleep curtailment, a common behavior in modern societies, is associated with sig-nificant alterations in metabolic and endocrine profiles. This pilot study aimed to investigate the potential benefits of sleep extension, under real-life conditions, on insulin sensitivity, an-drogens, and leptin, in women with habitual short sleep duration. Methods: In a single-arm study design, healthy pre-menopausal women with ≤ 6 hours of daily sleep (n=10) were in-structed to increase their sleep duration by one hour daily for one month. Fasting blood sam-ples were obtained on days 2-3 of the menstrual cycle, at baseline, and after the intervention. Samples were analyzed for glucose, insulin, leptin, total testosterone, sex hormone-binding globulin, and dehydroepiandrosterone-sulfate. Measurement of sleep duration was based on the participants' subjective reporting using sleep logs, and baseline data were compared to post-intervention. Results: Seven women completed the intervention and significantly in-creased their sleep duration by 40.7 ± 14 min (mean ± standard deviation). However, our pilot data did not indicate significant changes in any of the parameters assessed at the end of the intervention. Conclusion: The impact of sleep extension on various metabolic and androgen parameters in women requires further investigation with larger samples and more controlled designs.

Recommended Citation

Haj-Husein, I., Hamdan, N., & Ghazzawi, H. (2023). The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study. Palestinian Medical and Pharmaceutical Journal, 8(3), 337–342. https://doi.org/10.59049/2790-0231.1252
[1]I. Haj-Husein, N. Hamdan, and H. Ghazzawi, “The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study,” Palestinian Medical and Pharmaceutical Journal, vol. 8, no. 3, pp. 337–342, Dec. 2023, doi: 10.59049/2790-0231.1252.
Haj-Husein, Isra’a, et al. “The Effect of Sleep Extension on Metabolic and Androgen Parameters of Healthy Women with Habitual Short Sleep Duration: Pilot Study.” Palestinian Medical and Pharmaceutical Journal, vol. 8, no. 3, Dec. 2023, pp. 337–42. Crossref, https://doi.org/10.59049/2790-0231.1252.
1.Haj-Husein I, Hamdan N, Ghazzawi H. The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study. Palestinian Medical and Pharmaceutical Journal [Internet]. 2023 Dec;8(3):337–42. Available from: http://dx.doi.org/10.59049/2790-0231.1252
Haj-Husein, Isra’a, Nour Hamdan, and Hadeel Ghazzawi. “The Effect of Sleep Extension on Metabolic and Androgen Parameters of Healthy Women with Habitual Short Sleep Duration: Pilot Study.” Palestinian Medical and Pharmaceutical Journal 8, no. 3 (December 2023): 337–42. https://doi.org/10.59049/2790-0231.1252.

The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study

معلومات المقال

2022-01-14
2023-01-12
337 - 342

الكلمات الإفتتاحية

  • Sleep Curtailment; Insulin Resistance; Androgens
  • Leptin

الملخص

Aims: Sleep curtailment, a common behavior in modern societies, is associated with sig-nificant alterations in metabolic and endocrine profiles. This pilot study aimed to investigate the potential benefits of sleep extension, under real-life conditions, on insulin sensitivity, an-drogens, and leptin, in women with habitual short sleep duration. Methods: In a single-arm study design, healthy pre-menopausal women with ≤ 6 hours of daily sleep (n=10) were in-structed to increase their sleep duration by one hour daily for one month. Fasting blood sam-ples were obtained on days 2-3 of the menstrual cycle, at baseline, and after the intervention. Samples were analyzed for glucose, insulin, leptin, total testosterone, sex hormone-binding globulin, and dehydroepiandrosterone-sulfate. Measurement of sleep duration was based on the participants' subjective reporting using sleep logs, and baseline data were compared to post-intervention. Results: Seven women completed the intervention and significantly in-creased their sleep duration by 40.7 ± 14 min (mean ± standard deviation). However, our pilot data did not indicate significant changes in any of the parameters assessed at the end of the intervention. Conclusion: The impact of sleep extension on various metabolic and androgen parameters in women requires further investigation with larger samples and more controlled designs.

Recommended Citation

Haj-Husein, I., Hamdan, N., & Ghazzawi, H. (2023). The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study. Palestinian Medical and Pharmaceutical Journal, 8(3), 337–342. https://doi.org/10.59049/2790-0231.1252
[1]I. Haj-Husein, N. Hamdan, and H. Ghazzawi, “The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study,” Palestinian Medical and Pharmaceutical Journal, vol. 8, no. 3, pp. 337–342, Dec. 2023, doi: 10.59049/2790-0231.1252.
Haj-Husein, Isra’a, et al. “The Effect of Sleep Extension on Metabolic and Androgen Parameters of Healthy Women with Habitual Short Sleep Duration: Pilot Study.” Palestinian Medical and Pharmaceutical Journal, vol. 8, no. 3, Dec. 2023, pp. 337–42. Crossref, https://doi.org/10.59049/2790-0231.1252.
1.Haj-Husein I, Hamdan N, Ghazzawi H. The effect of sleep extension on metabolic and androgen parameters of healthy women with habitual short sleep duration: Pilot study. Palestinian Medical and Pharmaceutical Journal [Internet]. 2023 Dec;8(3):337–42. Available from: http://dx.doi.org/10.59049/2790-0231.1252
Haj-Husein, Isra’a, Nour Hamdan, and Hadeel Ghazzawi. “The Effect of Sleep Extension on Metabolic and Androgen Parameters of Healthy Women with Habitual Short Sleep Duration: Pilot Study.” Palestinian Medical and Pharmaceutical Journal 8, no. 3 (December 2023): 337–42. https://doi.org/10.59049/2790-0231.1252.

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Cite Score (Scopus): 0.8
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