Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.)

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Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.) Indexed in Scopus since 2022
CiteScore 1.0
Indexed since 2022
First decision 7 Days
Submission to acceptance 45 Days
Acceptance to publication 14 Days
Acceptance rate 8%

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Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.) Open directory record
Original full research article

An Overview of Nanocapsule and Lipid Nanocapsule: Recent Developments and Future Prospects

Published
2022-11-20
Pages
221 - 238
Full text

Keywords

  • Encapsulation
  • Emulsion
  • Nanocapsule
  • Drug delivery system
  • Capsule
  • Nanotechnology

Abstract

Nanocapsules are colloidal particles with dimensions measured in nanometers and gener-ally obtained in the range of 100 to 500 nm through nanoencapsulation technologies. Nano-encapsulation encapsulates nano-sized particles in liquid or solid form to create nanocapsules or nanoparticles. Generally, six classical methods are involved in nanocapsule formation: na-noprecipitation, emulsification-diffusion, double emulsification, emulsification-coacervation, polymer coating, and layer-by-layer. Nanocapsules are prepared from different monomers and cross-linked polymers, contributing to their stability during and after encapsulation. They are segregated into ionic and non-ionic by the surface formal charges, which then influence the type of applications. The applications of nanocapsules usually range from developing targeted drug delivery systems, self-healing materials, and the encapsulation of nutritive addi-tive compounds in nutraceutical products. Nowadays, people turn their attention to natural resources. Therefore, the polymer matrix and the active substances in nanocapsules have been adopted with various natural polymers such as protein, lipids, polysaccharides, plant metabolites, plant exudates, or plant extracts. Since nanotechnology products are predicted to be broadly utilized in the future, major key players must work collectively to handle the issue of safety regulation and user acceptance as well as optimum scale production of nanocap-sules in industries.

Article history

Received
2022-06-08
Accepted
2022-11-20
بحث أصيل كامل

An Overview of Nanocapsule and Lipid Nanocapsule: Recent Developments and Future Prospects

Published
2022-11-20
الصفحات
221 - 238
البحث كاملا

الكلمات الإفتتاحية

  • Encapsulation
  • Emulsion
  • Nanocapsule
  • Drug delivery system
  • Capsule
  • Nanotechnology

الملخص

Nanocapsules are colloidal particles with dimensions measured in nanometers and gener-ally obtained in the range of 100 to 500 nm through nanoencapsulation technologies. Nano-encapsulation encapsulates nano-sized particles in liquid or solid form to create nanocapsules or nanoparticles. Generally, six classical methods are involved in nanocapsule formation: na-noprecipitation, emulsification-diffusion, double emulsification, emulsification-coacervation, polymer coating, and layer-by-layer. Nanocapsules are prepared from different monomers and cross-linked polymers, contributing to their stability during and after encapsulation. They are segregated into ionic and non-ionic by the surface formal charges, which then influence the type of applications. The applications of nanocapsules usually range from developing targeted drug delivery systems, self-healing materials, and the encapsulation of nutritive addi-tive compounds in nutraceutical products. Nowadays, people turn their attention to natural resources. Therefore, the polymer matrix and the active substances in nanocapsules have been adopted with various natural polymers such as protein, lipids, polysaccharides, plant metabolites, plant exudates, or plant extracts. Since nanotechnology products are predicted to be broadly utilized in the future, major key players must work collectively to handle the issue of safety regulation and user acceptance as well as optimum scale production of nanocap-sules in industries.

Article history

تاريخ التسليم
2022-06-08
تاريخ القبول
2022-11-20