Palestinian Medical and Pharmaceutical Journal (Pal. Med. Pharm. J.)

Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine

Article info

2023-03-11
2023-04-28
2024-03-01
49 - 58

Keywords

  • Outcome
  • Unprotected
  • Left Main
  • Stenting

Abstract

Objective: The study aimed to assess the results of stenting in unprotected left main cor-onary artery disease (uLMCAD) at a tertiary hospital center. Methods: We assessed all pa-tients who received stenting for uLMCAD, including stable patients who underwent elective, urgent, or emergent procedures. Data were gathered by reviewing hospital records and coro-nary angiograms and calculating SYNTAX scores. Patient follow-up was conducted via clinic visits and phone calls. Results: Percutaneous coronary intervention (PCI) was performed on seventy patients with uLMCAD, all of whom had successful revascularization. During their hospital stay, only one patient (1.4%) died from a noncardiac cause and no patient experi-enced target lesion failure. After an average follow-up of 17.4 ± 12.36 months, four patients (5.7%) died, with three of the deaths being noncardiac. Eight patients (11.4%) also experi-enced major adverse cardiac events, and six (8.6%) required target vessel revascularization. The crush technique was associated with a lower rate of target lesion failure than the non-crush technique (0% vs. 14%, p=0.03). Furthermore, patients with one- to two-vessel disease had lower rates of target lesion failure than those with three-vessel disease (2.5% vs. 16.7%, p=0.048). Other variables, such as the Syntax score and the lesion site (distal and nondistal left main disease), did not appear to affect target lesion outcomes. Conclusions: In our cen-ter, the stenting procedure for uLMCAD resulted in favorable outcomes during hospitaliza-tion and at the long-term follow-up, comparable to the results of large clinical trials.

Recommended Citation

Daralammouri, Y., Hamayel, H., Yassin, R., Kittaneh, A., Asaly, A., Nazzal, Z., & Ismail, Y. (2024). Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine. Palestinian Medical and Pharmaceutical Journal, 9(1), 49–58. https://doi.org/10.59049/2790-0231.1119
[1]Y. Daralammouri et al., “Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine,” Palestinian Medical and Pharmaceutical Journal, vol. 9, no. 1, pp. 49–58, Mar. 2024, doi: 10.59049/2790-0231.1119.
Daralammouri, Yunis, et al. “Percutaneous Coronary Intervention in Unprotected Left Main Coronary Artery Stenosis Patients. A Retrospective Study from Palestine.” Palestinian Medical and Pharmaceutical Journal, vol. 9, no. 1, Mar. 2024, pp. 49–58. Crossref, https://doi.org/10.59049/2790-0231.1119.
1.Daralammouri Y, Hamayel H, Yassin R, Kittaneh A, Asaly A, Nazzal Z, et al. Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine. Palestinian Medical and Pharmaceutical Journal [Internet]. 2024 Mar;9(1):49–58. Available from: http://dx.doi.org/10.59049/2790-0231.1119
Daralammouri, Yunis, Hamza Hamayel, Raya Yassin, Ameer Kittaneh, Aya Asaly, Zaher Nazzal, and Yahya Ismail. “Percutaneous Coronary Intervention in Unprotected Left Main Coronary Artery Stenosis Patients. A Retrospective Study from Palestine.” Palestinian Medical and Pharmaceutical Journal 9, no. 1 (March 2024): 49–58. https://doi.org/10.59049/2790-0231.1119.

Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine

معلومات المقال

2023-03-11
2023-04-28
2024-03-01
49 - 58

الكلمات الإفتتاحية

  • Outcome
  • Unprotected
  • Left Main
  • Stenting

الملخص

Objective: The study aimed to assess the results of stenting in unprotected left main cor-onary artery disease (uLMCAD) at a tertiary hospital center. Methods: We assessed all pa-tients who received stenting for uLMCAD, including stable patients who underwent elective, urgent, or emergent procedures. Data were gathered by reviewing hospital records and coro-nary angiograms and calculating SYNTAX scores. Patient follow-up was conducted via clinic visits and phone calls. Results: Percutaneous coronary intervention (PCI) was performed on seventy patients with uLMCAD, all of whom had successful revascularization. During their hospital stay, only one patient (1.4%) died from a noncardiac cause and no patient experi-enced target lesion failure. After an average follow-up of 17.4 ± 12.36 months, four patients (5.7%) died, with three of the deaths being noncardiac. Eight patients (11.4%) also experi-enced major adverse cardiac events, and six (8.6%) required target vessel revascularization. The crush technique was associated with a lower rate of target lesion failure than the non-crush technique (0% vs. 14%, p=0.03). Furthermore, patients with one- to two-vessel disease had lower rates of target lesion failure than those with three-vessel disease (2.5% vs. 16.7%, p=0.048). Other variables, such as the Syntax score and the lesion site (distal and nondistal left main disease), did not appear to affect target lesion outcomes. Conclusions: In our cen-ter, the stenting procedure for uLMCAD resulted in favorable outcomes during hospitaliza-tion and at the long-term follow-up, comparable to the results of large clinical trials.

Recommended Citation

Daralammouri, Y., Hamayel, H., Yassin, R., Kittaneh, A., Asaly, A., Nazzal, Z., & Ismail, Y. (2024). Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine. Palestinian Medical and Pharmaceutical Journal, 9(1), 49–58. https://doi.org/10.59049/2790-0231.1119
[1]Y. Daralammouri et al., “Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine,” Palestinian Medical and Pharmaceutical Journal, vol. 9, no. 1, pp. 49–58, Mar. 2024, doi: 10.59049/2790-0231.1119.
Daralammouri, Yunis, et al. “Percutaneous Coronary Intervention in Unprotected Left Main Coronary Artery Stenosis Patients. A Retrospective Study from Palestine.” Palestinian Medical and Pharmaceutical Journal, vol. 9, no. 1, Mar. 2024, pp. 49–58. Crossref, https://doi.org/10.59049/2790-0231.1119.
1.Daralammouri Y, Hamayel H, Yassin R, Kittaneh A, Asaly A, Nazzal Z, et al. Percutaneous coronary intervention in unprotected left main coronary artery stenosis patients. A Retrospective Study from Palestine. Palestinian Medical and Pharmaceutical Journal [Internet]. 2024 Mar;9(1):49–58. Available from: http://dx.doi.org/10.59049/2790-0231.1119
Daralammouri, Yunis, Hamza Hamayel, Raya Yassin, Ameer Kittaneh, Aya Asaly, Zaher Nazzal, and Yahya Ismail. “Percutaneous Coronary Intervention in Unprotected Left Main Coronary Artery Stenosis Patients. A Retrospective Study from Palestine.” Palestinian Medical and Pharmaceutical Journal 9, no. 1 (March 2024): 49–58. https://doi.org/10.59049/2790-0231.1119.

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Cite Score (Scopus): 0.8
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